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Smarter Bioprocessing Starts Here: Explore the Cytiva x Culture Global Collaboration

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Applications

Synthetic biology applications

Streamline fermentation for synthetic biology with or without a lab

Synthetic biology companies rely on efficient fermentation processes, strain optimization, and scalable bioprocessing to bring innovations to market. We offer two powerful solutions: our cloud-connected 250mL and 5L bioreactor service, providing high-throughput, managed fermentation capacity, and Stratyx250 - a disposable 250mL bioreactor for in-house experimentation. Whether refining microbial fermentation solutions, conducting strain screening, or optimizing synthetic biology applications, our flexible solutions can help you accelerate process development without costly infrastructure investments.

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Benefits

 
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Scale fermentation without infrastructure delays

Skip the time and cost of lab build-outs. Our cloud-connected bioreactors (250mL and 5L) provide on-demand fermentation capacity, while Stratyx250 enables in-house process testing for early-stage development.

Optimize strain performance faster
Optimize strain performance faster

Leverage our managed strain screening services with cloud bioreactors or integrate Stratyx250 into your own lab for rapid strain selection and microbial fermentation process refinement. With over 20,000 fermentation runs across P. pastoris, E.coli, B. subtilis, filamentous fungi, and S. cerevisiae, our team offers their expertise in strain screening and fermentation optimization to ensure precision throughout every test.

 
Increase speed to manufacturing milestones
Increase speed to manufacturing milestones

Save 6-18 months by outsourcing bioprocess development to our high-throughput cloud bioreactors, or use Stratyx250 to optimize fermentation conditions before scaling up.

Capabilities

 
Scalable strain screening for synthetic biology
Scalable strain screening for synthetic biology

Expand your strain screening capacity using our cloud-connected bioreactors or Stratyx250’s in-house disposable bioreactor. Our proven strain screening workflow optimizes microbial strains for metabolic engineering, enzyme production, and synthetic biology applications—giving you the flexibility to screen strains in your own lab or with our managed service.

In-house microbial analytics for faster process development
In-house microbial analytics for faster process development

Gain deeper insights into synthetic biology fermentation processes with real-time microbial analytics. Our cloud bioreactors provide remote monitoring and automated data collection, while Stratyx250 offers in-lab analysis of biomass, metabolites, oxygen and CO2 of gas, and residual substrate levels, allowing you to track process performance wherever you operate.

 
Run large DOEs for process optimization
Run large DOEs for process optimization

Optimize and refine synthetic biology pathways with large-scale design of experiments (DOEs). Our automated cloud bioreactors support high-throughput fermentation and advanced data analytics, while Stratyx250 allows for in-house testing of DOE parameters before transitioning to larger-scale workflows.

Service packages

Whether you want to work with Culture on a continuous or per project basis, we have a service package tailored to your specific goals.

Clone, strain & construct screening

Evaluate your bio clones, strains, and viral constructs with scalable flexibility using our advanced cell culture bioreactors. Our platform ensures efficient clone screening systems for optimal performance.

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Process development

Accelerate timelines, optimize performance, and reduce risks in bringing biotherapeutics to market with our upstream process development services and advanced bioreactor technology. By focusing on cell culture media optimization and development, we can help ensure your experiments deliver efficient and reproducible outcomes.

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Process characterization

Use our advanced bioreactors and Design of Experiments (DoE) expertise to perform cell culture process characterization prior to PPQ. Assess your upstream process in scale-down bioreactors that allow for enhanced model curvature, deeper variable exploration, and more robust process characterization development.

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Bioprocess modeling and simulation

Scaling a bioprocess from R&D to manufacturing is challenging. Bioprocess modeling and simulation enables precise control over process conditions, improving efficiency and reducing variability. Our services offer a bioprocess digital twin approach to streamline development, leveraging advanced modeling to simulate and optimize conditions before running costly experiments.

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Bioreactor scale-out

Run multiple experiments using our parallel bioreactor systems, which are cloud-connected 250mL and 5L bioreactors managed in our facility for high-throughput optimization to ensure process consistency, accelerated development, and seamless scalability. For those seeking an in-house solution, Stratyx250 provides a disposable 250mL bioreactor that users can implement directly in their own labs for greater control. While you will be limited on the number of experiments you can run on your own, you can pair our Stratyx platform running in your lab with the bioreactors running in ours. 

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BLOG

Latest resources

Advanced Therapies Week 2026: Demonstrating Bioprocessing Anytime, Anywhere
Blog post

Advanced Therapies Week 2026: Demonstrating Bioprocessing Anytime, Anywhere

March 6, 2026
Culture Biosciences Announces Close of Series C Round to Accelerate Commercial Growth of Stratyx 250 and Console Platform
Press

Culture Biosciences Announces Close of Series C Round to Accelerate Commercial Growth of Stratyx 250 and Console Platform

December 16, 2025

Optimize your bioprocess with Culture