--- title: Advanced Process Characterization for Bioprocessing Teams description: Improve your cell culture process characterization with our scalable bioprocessing services. Improve consistency, insight & optimization at every stage. image: https://www.culturebiosciences.com/hubfs/Website%202026/Images/process-characterization-hero.webp --- [Skip to main content](https://www.culturebiosciences.com/services/process-characterization#main-content) [![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg) ![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20white.svg) ![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg)](https://www.culturebiosciences.com?hsLang=en) - Show submenu for Products Products - [Console Software](https://www.culturebiosciences.com/-console) - [Stratyx Bioreactor](https://www.culturebiosciences.com/stratyx) - [Services](https://www.culturebiosciences.com/nexxys) - Show submenu for Resources Resources - [White Papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Technical Bulletins](https://www.culturebiosciences.com/resources/tag/technical-bulletin) - [Case Studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog Posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Posters](https://www.culturebiosciences.com/resources/tag/poster) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [View All](https://www.culturebiosciences.com/resources) - [About](https://www.culturebiosciences.com/about) Open main navigation Close main navigation - Show submenu for Products Products - Products - [Console Software](https://www.culturebiosciences.com/-console) - [Stratyx Bioreactor](https://www.culturebiosciences.com/stratyx) - [Services](https://www.culturebiosciences.com/nexxys) - Show submenu for Resources Resources - Resources - [White Papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Technical Bulletins](https://www.culturebiosciences.com/resources/tag/technical-bulletin) - [Case Studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog Posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Posters](https://www.culturebiosciences.com/resources/tag/poster) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [View All](https://www.culturebiosciences.com/resources) - [About](https://www.culturebiosciences.com/about) - [Login](https://console.culturebiosciences.com/login) [Contact](https://www.culturebiosciences.com/contact) [Login](https://console.culturebiosciences.com/login) [Contact](https://www.culturebiosciences.com/contact?hsLang=en) Services # Process characterization [See Sample Data](https://www.culturebiosciences.com/resources/milliporesigma-achieved-significant-increases-in-the-final-titers-for-multiple-chozn-r-cell-lines-using-culture-biosciences-cloud-bioreactor-platform?hsLang=en) ### Accelerate process characterization development and cell culture optimization with scalable, data-driven experimentation. Use our advanced bioreactors and Design of Experiments (DoE) expertise to perform cell culture process characterization prior to PPQ. Assess your upstream process in scale-down bioreactors that allow for enhanced model curvature, deeper variable exploration, and more robust process characterization development. ![clone-hero-250](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/clone-hero-250.webp?width=800&height=533&name=clone-hero-250.webp) ![process-characterization-hero](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/process-characterization-hero.webp?width=800&height=518&name=process-characterization-hero.webp) ## Benefits   ![Culture\_Icon\_Data\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Data_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Data_Expressive_Green_01.png) ##### Debottleneck cell culture process characterization Leverage a high-throughput platform built for process characterization. Our large fleet of custom bioreactors and experienced team help you run extensive DoE studies to define Critical Process Parameters (CPPs) efficiently and cost-effectively. ![Culture\_Icon\_Data\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Data_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Data_Expressive_Green_01.png) ##### Transparent, real-time cell culture optimization data Access real-time insights with our cloud-connected bioreactors. Live monitoring of your cell culture process characterization runs allows for faster iteration, better decision-making, and more confident downstream transfer. Gain full visibility into experimental performance at every stage.   ![Culture\_Icon\_Data\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Data_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Data_Expressive_Green_01.png) ##### Avoid large, upfront CAPEX and FTE training Outsource your process characterization development to Culture’s team instead of investing in lab build-outs, capital equipment, and staff training. Our infrastructure allows you to focus resources on decision-making, not setup. ## Capabilities   ![Culture\_Icon\_Duplicate\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Duplicate_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Duplicate_Expressive_Green_01.png) ##### Run extensive DOEs We support high-volume DoE execution for cell culture optimization and process characterization development, including multi-factor screening, interaction modeling, and late-stage refinement. ![Culture\_Icon\_Duplicate\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Duplicate_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Duplicate_Expressive_Green_01.png) ##### Cloud-connected, real-time monitoring Track every run in real time via our cloud-based platform. Monitor variables, trends, and performance metrics instantly during cell culture process characterization, gaining unparalleled control over your upstream experimentation.   ![Culture\_Icon\_Duplicate\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Duplicate_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Duplicate_Expressive_Green_01.png) ##### DOE design and data analysis support Our data science team brings deep expertise in statistical modeling, power analysis, and outcome interpretation. Let us help design your process characterization studies and extract actionable insights. ## Having access to Culture’s Cloud Lab has allowed us to pursue multiple projects simultaneously. ![darcy-prather](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/darcy-prather.jpeg?width=232&height=232&name=darcy-prather.jpeg) Darcy Prather Co-founder and President, *Kalion* ## Our facility Our laboratories based in San Francisco are equipped with segregated modality suites, state-of-the-art bioreactors and analytical instrumentation, all operated by an experienced bioprocess development team. ![facility-1](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/facility-1.png?width=647&height=675&name=facility-1.png) ![facility-2](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/facility-2.png?width=648&height=330&name=facility-2.png) ![facility-3](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/facility-3.png?width=648&height=330&name=facility-3.png) ### 350+ 250mL and 5L bioreactors ### 20,000+ Bioreactor runs to date ### 70+ Customers have used Culture's services to date ## High quality & safety standards ##### Analytical capabilities - **Microbial bioprocess** \- Biomass quantification \- Metabolite analysis - **Mammalian bioprocess** \- Viability and cell counts \- Metabolite analysis - Host cell protein - **Protein** \- Titer quantification \- Monomer/aggregation quantification - **Viral vector** \- Capsid titer \- Viral genome titer \- Empty/full ratio ##### Segregated modality suites - **Mammalian** CHO and HEK - **Viral vector (AAV)** AAV generated by HEK transfection - **Microbial** Yeast, bacteria, and fungi - **Media** Media recipes to customer specifications ##### Rigorous standards - **Quality management systems (QMS)** Quality review of all runs and CAPA for major deviations - **Safety & security** BSL-2 and SOC2 compliant ## Our bioreactors At Culture, we custom-build our reactors to be cloud-connected and modular, making bioprocess scale-out, design, monitoring, and analysis as easy as possible. ### 250mL bench-scale single-use bioreactor Benchtop bioreactor for process development [Learn more](https://www.culturebiosciences.com/bioreactors/250ml?hsLang=en) ### 5L single-use bioreactor Our modular bioreactors are designed to be easily scaled up or down. [Learn more](https://www.culturebiosciences.com/bioreactors/5l?hsLang=en) ## Explore our other service packages ### Clone, strain & construct screening Clone, strain & construct screening in our bioreactors [Learn more](https://www.culturebiosciences.com/services/clone-strain-and-construct-screening?hsLang=en) ### Process development Upstream process development and optimization [Learn more](https://www.culturebiosciences.com/services/process-development?hsLang=en) ### Bioprocess modeling and simulation Create bioprocess digital twins for scalable biomanufacturing in collaboration with our data science team [Learn more](https://www.culturebiosciences.com/services/process-model-development?hsLang=en) ### Bioreactor scale-out Leverage bioreactor capacity when you need it [Learn more](https://www.culturebiosciences.com/services/scale-out-capacity?hsLang=en) ## Optimize your bioprocess with Culture [Schedule demo](https://www.culturebiosciences.com/request-demo?hsLang=en) ![Culture Logo black](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg) ### Sign up for our newsletter and grow your insights with Culture. 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