Applications

Protein therapeutics

Accelerate and expand your protein therapeutic pipeline with Culture

Culture accelerates and de-risks process development, process characterization, material generation, and modeling for protein therapeutics in our cloud-connected bioreactor facility. By providing scalable protein therapeutic production solutions and efficient protein expression systems, we empower biotech researchers, pharmaceutical teams, and startups to rapidly optimize their processes and achieve consistent results. With Culture, you gain access to advanced tools and expertise that streamline upstream therapeutics.

Bioreactor with media - Culture Bioscience

Benefits

Increase speed to clinic and manufacturing milestones

Save 6-18 months in your protein therapeutic development timeline with access to our cloud-connected bioreactor facility. Instead of dedicating time and resources to building your own lab infrastructure, focus on advancing your protein therapeutic pipeline. Our streamlined workflows and advanced systems are purpose-built to accelerate key milestones in clinic and manufacturing, helping you bring innovative therapies to market faster.

Scale-out without the delays of lab build, investment, and staffing

Avoid the costly and time-consuming challenges of constructing a dedicated process development facility. With Culture, you can run process development or characterization Design of Experiments (DOEs) on-demand, without the delays associated with hiring specialized staff or securing significant capital investments. Our platform enables you to scale-out with efficiency, supporting your team in generating valuable insights and data at a fraction of the time.

Purpose-built to support protein therapeutic upstream process development

Our bioreactors are specifically designed for high-density, fed-batch microbial and mammalian upstream therapeutics processes, making them ideal for protein therapeutic development. Whether you are working on early-stage process optimization or scaling for production, our platform delivers precise control and consistency, ensuring robust and reliable upstream results. This specialized design helps biotech and pharmaceutical teams achieve superior outcomes with less effort and complexity.

Capabilities

Modality suites for a range of cell lines

We offer comprehensive expertise across a wide variety of cell lines, including CHO, HEK, yeast, and E. coli, as well as many other platforms commonly used in protein therapeutic production. Our versatile modality suites are designed to support diverse biological systems, enabling seamless adaptation to the unique requirements of your project. Whether you’re working with mammalian cells for complex protein expression or microbial systems for high-yield production, our tailored solutions ensure reliable scalability and efficiency throughout your process.

Services tailored to clinical stage

Whether you’re in preclinical development or preparing for late-phase clinical trials, we offer a full range of services to meet your specific needs. From clone screening for early-stage development to detailed process characterization for regulatory submission, our platform supports every step of your journey. With flexible, scalable solutions designed for clinical-stage protein therapeutics, efficiently navigate the complexities of process development and achieve key milestones with confidence.

In-house protein analytics for faster process development

Accelerate your development timelines with our integrated protein analytics. Culture provides in-house tools such as Size Exclusion Chromatography (SEC) for detailed product attribute analysis, IgG titer measurements for rapid quality assessments, and protein mass spectroscopy to precisely characterize molecular weight and structural integrity. We also offer process monitoring capabilities, including viable cell density (VCD), pH, and metabolite tracking, to deliver real-time insights into process performance. By combining analytical precision with process expertise, we help you optimize your workflows and achieve consistent, high-quality results.

When you’re developing a new protein technology and the production process for it, you really can’t overestimate the importance of access to lab-scale fermenters.
Alex Lorestani
Blog

Latest resources

Announcement

Culture Biosciences unveils Stratyx™ 250, the first cloud-integrated, mobile bioreactor for cell culture process development

April 1, 2025
Documentation

Stratyx™ 250 Hardware & Single Use Technical Specifications

April 1, 2025

Optimize your bioprocess with Culture