--- title: Run Remote Bioprocess Experiments in 250mL Bioreactors description: Conduct high-throughput upstream experiments remotely in our 250mL benchtop bioreactors. Cloud monitoring for mammalian, microbial & viral vector development. image: https://www.culturebiosciences.com/hubfs/Website%202026/Images/bioreactior-250ml.webp --- [Skip to main content](https://www.culturebiosciences.com/bioreactors/250ml#main-content) [![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg) ![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20white.svg) ![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg)](https://www.culturebiosciences.com?hsLang=en) - Show submenu for Products Products - [Console Software](https://www.culturebiosciences.com/-console) - [Stratyx Bioreactor](https://www.culturebiosciences.com/stratyx) - [Services](https://www.culturebiosciences.com/nexxys) - Show submenu for Resources Resources - [White Papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Technical Bulletins](https://www.culturebiosciences.com/resources/tag/technical-bulletin) - [Case Studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog Posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Posters](https://www.culturebiosciences.com/resources/tag/poster) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [View All](https://www.culturebiosciences.com/resources) - [About](https://www.culturebiosciences.com/about) Open main navigation Close main navigation - Show submenu for Products Products - Products - [Console Software](https://www.culturebiosciences.com/-console) - [Stratyx Bioreactor](https://www.culturebiosciences.com/stratyx) - [Services](https://www.culturebiosciences.com/nexxys) - Show submenu for Resources Resources - Resources - [White Papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Technical Bulletins](https://www.culturebiosciences.com/resources/tag/technical-bulletin) - [Case Studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog Posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Posters](https://www.culturebiosciences.com/resources/tag/poster) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [View All](https://www.culturebiosciences.com/resources) - [About](https://www.culturebiosciences.com/about) - [Login](https://console.culturebiosciences.com/login) [Contact](https://www.culturebiosciences.com/contact) [Login](https://console.culturebiosciences.com/login) [Contact](https://www.culturebiosciences.com/contact?hsLang=en) Our Bioreactors # 250mL bench-scale single-use bioreactor [Request demo](https://www.culturebiosciences.com/contact?hsLang=en) ## Benchtop bioreactor for process development Culture's 250mL single-use bioreactors are tailored for early-stage bioprocessing, providing an ideal platform for high-throughput screening, [clone screening](https://www.culturebiosciences.com/services/clone-strain-and-construct-screening?hsLang=en), and microbial fermentation. These small-batch bioreactors are designed to support mammalian cell culture, microbial, and viral vector development, offering precision for small-scale bioprocess optimization in R&D settings. Perfect for researchers working on small-scale projects, our 250mL benchtop bioreactors streamline early-stage experiments and allow for seamless scale-up. With a wide range of applications in [process development](https://www.culturebiosciences.com/services/process-development?hsLang=en), process optimization, and [process characterization](https://www.culturebiosciences.com/services/process-characterization?hsLang=en), they are an essential tool for advancing from early-stage bioprocessing to larger-scale production. ![bioreactior-250ml](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/bioreactior-250ml.webp?width=1272&height=1468&name=bioreactior-250ml.webp) ## Key Benefits of the STRATYX 250 [Download full specs](https://share.hsforms.com/1JXnE4E7CTF-YpjRgxtv-4Qpzz26) Microbial Mammalian - [Mammalian](https://www.culturebiosciences.com/bioreactors/250ml#mammalian) - [Microbial](https://www.culturebiosciences.com/bioreactors/250ml#microbial) - [Mammalian](https://www.culturebiosciences.com/bioreactors/250ml#mammalian) - [Microbial](https://www.culturebiosciences.com/bioreactors/250ml#microbial) Microbial ![250ml-mammal](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/250ml-mammal.webp?width=1000&height=542&name=250ml-mammal.webp) #### 165 kLa Maximum #### 12,000 P/V Maximum #### 0-14 pH #### Air, N2, CO2, O2 Gasses #### Pitched blade, 2x24 mm Impeller type ![250ml-microb](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/250ml-microb.webp?width=1514&height=820&name=250ml-microb.webp) #### 450 kLa Maximum #### 62,000 P/V Maximum #### 0-14 pH #### Air, N2, CO2, O2 Gasses #### Pitched blade, 2x24 mm Impeller type ## Related resources [![Extending Bioprocess Development with Nexxys](https://www.culturebiosciences.com/hs-fs/hubfs/White%20Paper%20Feature%20%E2%80%93%20Gradient%20Background%20(7).png?width=500&height=380&name=White%20Paper%20Feature%20%E2%80%93%20Gradient%20Background%20(7).png)](https://www.culturebiosciences.com/resources/extending-bioprocess-development-with-nexxys?hsLang=en) Technical Bulletin ### [Extending Bioprocess Development with Nexxys](https://www.culturebiosciences.com/resources/extending-bioprocess-development-with-nexxys?hsLang=en) September 29, 2026 [Read More](https://www.culturebiosciences.com/resources/extending-bioprocess-development-with-nexxys?hsLang=en) [![AAV9 Process Robustness Evaluation in Cloud-Native 250mL Bioreactors](https://www.culturebiosciences.com/hs-fs/hubfs/White%20Paper%20Feature%20%E2%80%93%20Gradient%20Background%20(9).png?width=500&height=380&name=White%20Paper%20Feature%20%E2%80%93%20Gradient%20Background%20(9).png)](https://www.culturebiosciences.com/resources/aav9-process-robustness-evaluation-in-cloud-native-250ml-bioreactors-1?hsLang=en) Technical Bulletin ### [AAV9 Process Robustness Evaluation in Cloud-Native 250mL Bioreactors](https://www.culturebiosciences.com/resources/aav9-process-robustness-evaluation-in-cloud-native-250ml-bioreactors-1?hsLang=en) September 29, 2026 [Read More](https://www.culturebiosciences.com/resources/aav9-process-robustness-evaluation-in-cloud-native-250ml-bioreactors-1?hsLang=en) ## Frequently asked questions ### How well does your 250mL bioreactor scale to larger formats? Our 250mL bioreactors are specifically designed for smooth scalability. We offer a direct scale-up pathway to our 5L bioreactors, ensuring consistent results across both configurations. Additionally, our bioreactors have been successfully scaled to larger systems, including Cytiva platforms. For detailed scalability insights, consult the [Cytiva bioreactor scaling tool](https://www.cytivalifesciences.com/en/us/solutions/bioprocessing/products-and-solutions/upstream-bioprocessing/single-use-bioreactors/digital-bioreactor-scaling-tool). ### What materials are used in the construction of the 250mL bioreactor? The 250mL bioreactors are built using high-quality materials, including polycarbonate, polypropylene, stainless steel 316, and nylon, ensuring robustness and compatibility with diverse bioprocessing applications. For more detailed information, please refer to our [Technical Specifications](https://www.culturebiosciences.com/resources/technical-specifications?hsLang=en) document. ### What is the minimum and maximum working volume for the 250mL bioreactor? The working volume for the 250mL bioreactor ranges from 80mL to 250mL, providing flexibility for small-batch processes and early-stage bioprocessing. For more detailed specifications, please refer to our [Technical Specifications](https://www.culturebiosciences.com/resources/technical-specifications?hsLang=en) document. ## Explore our other bioreactors ### 5L single-use bioreactor Our modular bioreactors are designed to be easily scaled up or down. [Learn more](https://www.culturebiosciences.com/bioreactors/5l?hsLang=en) ## Optimize your bioprocess with Culture [Schedule demo](https://www.culturebiosciences.com/request-demo?hsLang=en) ![Culture Logo black](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg) ### Sign up for our newsletter and grow your insights with Culture. Smarter bioprocessing starts here. - Services Packages - [Clone, strain and construct screening](https://www.culturebiosciences.com/services/clone-strain-and-construct-screening) - [Process characterization](https://www.culturebiosciences.com/services/process-characterization) - [Process development](https://www.culturebiosciences.com/services/process-development) - [Bioprocess modeling
and simulation](https://www.culturebiosciences.com/services/process-model-development) - Products - [StratyxTM Bioreactor](https://www.culturebiosciences.com/stratyx) - [Console Software](https://www.culturebiosciences.com/#console) - [NexxysTM](https://www.culturebiosciences.com/nexxys) - [250mL bench-scale single-use bioreactor](https://www.culturebiosciences.com/bioreactors/250ml) - [5L single-use bioreactor](https://www.culturebiosciences.com/bioreactors/5l) - Applications - [Synthetic biology applications](https://www.culturebiosciences.com/applications/synthetic-biology) - [Protein therapeutics](https://www.culturebiosciences.com/applications/protein-therapeutics) - [Viral vectors](https://www.culturebiosciences.com/applications/viral-vectors) - Resources - [White papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Case studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [All resources](https://www.culturebiosciences.com/resources) - Company - [About](https://www.culturebiosciences.com/about) - [Careers](https://www.culturebiosciences.com/careers) - [Contact](https://www.culturebiosciences.com/contact) - [LinkedIn](https://www.linkedin.com/company/18240703/admin/feed/posts/) All systems operational... © 2026 Culture Biosciences [Terms](https://www.culturebiosciences.com/terms-of-service?hsLang=en) [Privacy](https://www.culturebiosciences.com/privacy-policy?hsLang=en) ```json { "@context" : "https://schema.org", "@type" : "FAQPage", "mainEntity" : [ { "@type" : "Question", "acceptedAnswer" : { "@type" : "Answer", "text" : "Our 250mL bioreactors are specifically designed for smooth scalability. We offer a direct scale-up pathway to our 5L bioreactors, ensuring consistent results across both configurations. Additionally, our bioreactors have been successfully scaled to larger systems, including Cytiva platforms. For detailed scalability insights, consult the Cytiva bioreactor scaling tool." }, "name" : "How well does your 250mL bioreactor scale to larger formats?" }, { "@type" : "Question", "acceptedAnswer" : { "@type" : "Answer", "text" : "The 250mL bioreactors are built using high-quality materials, including polycarbonate, polypropylene, stainless steel 316, and nylon, ensuring robustness and compatibility with diverse bioprocessing applications. For more detailed information, please refer to our Technical Specifications document." }, "name" : "What materials are used in the construction of the 250mL bioreactor?" }, { "@type" : "Question", "acceptedAnswer" : { "@type" : "Answer", "text" : "The working volume for the 250mL bioreactor ranges from 80mL to 250mL, providing flexibility for small-batch processes and early-stage bioprocessing. For more detailed specifications, please refer to our Technical Specifications document." }, "name" : "What is the minimum and maximum working volume for the 250mL bioreactor?" } ] } ```