Services

Process development

Process optimization and development

Execute media screening and process optimization experiments to improve your process.

Scientist with bioreactorsScientists with bioreactors

Benefits

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Debottleneck and accelerate process development

Run overflow projects and conduct parallel experiments with Culture to reduce development time and alleviate bottlenecks to project milestones.

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Run right-sized DOEs

Our platform supports DOEs as large as you need for comprehensive screening and process optimization.

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Real-time data via cloud-connected process monitoring software

Technology transfer is easy with cloud-connected, real-time data.

Capabilities

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Flexible capacity

Our fleet of bioreactors is configurable to run multi-factor DOEs of nearly any size.

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DOE design and data analysis support

Culture’s team of data scientists can help with DOE design, power analysis and experimental outcome analysis.

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Material generation

Generate material for downstream, drug product, and analytical activities. Outsource routine material supply to supplement your upstream bioreactor capacity.

Having access to Culture’s Cloud Lab has allowed us to pursue multiple projects simultaneously.
Darcy Prather

Our facility

Our laboratories based in San Francisco are equipped with segregated modality suites, state-of-the-art bioreactors and analytical instrumentation, all operated by an experienced bioprocess development team.

group of scientists with Bioreactors - Culture BioBioreactor - Culture BioBioreactor Lab - Culture Bio

350+

250mL and 5L bioreactors

20,000+

Bioreactor runs to date

70+

Customers have used Culture's services to date

High quality & safety standards

Analytical capabilities

Microbial bioprocess
- Biomass quantification
- Metabolite analysis
Mammalian bioprocess
- Viability and cell counts

- Metabolite analysis
- Host cell protein
Protein
- Titer quantification
- Monomer/aggregation quantification
Viral vector
- Capsid titer
- Viral genome titer
- Empty/full ratio

Segregated modality suites

Mammalian
CHO and HEK
Viral vector (AAV)
AAV generated by HEK transfection
Microbial
Yeast, bacteria, and fungi
Media
Media recipes to customer specifications

Rigorous standards

Quality management systems (QMS)
Quality review of all runs and CAPA for major deviations
Safety & security
BSL-2 and SOC2 compliant

Our bioreactors

At Culture, we custom-build our modular reactors with cloud-connected controllers, making bioprocess scale-out, design, monitoring, and analysis as easy as possible.

250mL bench-scale single-use bioreactor

Bioreactor for process development

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5L single-use bioreactor

Bioreactor for process development and material generation

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Culture in your lab

Modular single-use bioreactors designed to be easily scaled up or down

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Optimize your bioprocess with Culture