Accelerate timelines, optimize performance, and reduce risks in bringing biotherapeutics to market with our upstream process development services and advanced bioreactor technology. By focusing on cell culture media optimization and development, we can help ensure your experiments deliver efficient and reproducible outcomes.
Cell culture media optimization and development is critical to achieving efficient and reproducible outcomes in upstream bioprocessing. Our cutting-edge technology and deep expertise is combined to help you maximize productivity and ensure consistent performance at scale.
Using our DOE methodology, we accelerate the development process by testing multiple variables simultaneously. This approach provides data-driven insights to help shorten development timelines, reduce variability across experiments, and scale formulations from lab to production environments.
Finally, we support cell culture media optimization and development across various systems, including CHO Cells, HEK Cells, and Yeast and Microbial Systems.
We work with you to design, test, and refine media formulations tailored to your cell lines and production goals. Using our cloud-connected bioreactors, we can evaluate nutrient profiles to enhance growth and protect yields, test feed strategies to maintain cell health in high-density cultures, and identify and optimize critical media components to improve performance.
Cloud-connected bioreactors enable real-time monitoring of cell culture experiments for hastened optimization of critical process parameters. The power and outcome analysis ensure media is optimized for consistent and high-performing results.
Real-time monitoring, data collection, and precise control improve experimental outcomes and scalability.
Advanced monitoring tools for power and experimental outcome analysis enable assessment of critical process parameters - such as growth rates, metabolite profiles, and protein yields - to promote data-driven decision-making.
Our fleet of bioreactors is configurable to run multi-factor DOEs of nearly any size, applying systematic and data-driven experimental design to optimize bioprocess parameters efficiently and reduce variability across experiments.
Simultaneously test multiple variables to refine processes faster and more efficiently.
Tailored support for formulating, testing, and scaling cell culture media to maximize productivity and reproducibility.
Access a team of experienced bioprocess scientists to design, execute, and refine experiments for optimal outcomes.
Co-founder and President, Kalion
Our laboratories based in San Francisco are equipped with segregated modality suites, state-of-the-art bioreactors and analytical instrumentation, all operated by an experienced bioprocess development team.
Our modular bioreactors are designed to be easily scaled up or down.
