--- title: Clone Screening & Strain Bio Services | Bioreactors description: Screen bio clones and cell strains efficiently with our automated clone screening systems—ideal for construct evaluation, optimization & scale-up. image: https://www.culturebiosciences.com/hubfs/Website%202026/Images/clone-hero.webp --- [Skip to main content](https://www.culturebiosciences.com/services/clone-strain-and-construct-screening#main-content) [![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg) ![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20white.svg) ![Culture Biosciences](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg)](https://www.culturebiosciences.com?hsLang=en) - Show submenu for Products Products - [Console Software](https://www.culturebiosciences.com/-console) - [Stratyx Bioreactor](https://www.culturebiosciences.com/stratyx) - [Services](https://www.culturebiosciences.com/nexxys) - Show submenu for Resources Resources - [White Papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Technical Bulletins](https://www.culturebiosciences.com/resources/tag/technical-bulletin) - [Case Studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog Posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Posters](https://www.culturebiosciences.com/resources/tag/poster) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [View All](https://www.culturebiosciences.com/resources) - [About](https://www.culturebiosciences.com/about) Open main navigation Close main navigation - Show submenu for Products Products - Products - [Console Software](https://www.culturebiosciences.com/-console) - [Stratyx Bioreactor](https://www.culturebiosciences.com/stratyx) - [Services](https://www.culturebiosciences.com/nexxys) - Show submenu for Resources Resources - Resources - [White Papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Technical Bulletins](https://www.culturebiosciences.com/resources/tag/technical-bulletin) - [Case Studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog Posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Posters](https://www.culturebiosciences.com/resources/tag/poster) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [View All](https://www.culturebiosciences.com/resources) - [About](https://www.culturebiosciences.com/about) - [Login](https://console.culturebiosciences.com/login) [Contact](https://www.culturebiosciences.com/contact) [Login](https://console.culturebiosciences.com/login) [Contact](https://www.culturebiosciences.com/contact?hsLang=en) Services # Clone, strain & construct screening [See Sample Data](https://www.culturebiosciences.com/resources/a-guide-for-running-statistically-powered-clone-screening-experiments?hsLang=en) ## Clone, strain & construct screening in our bioreactors Evaluate your bio clones, strains, and viral constructs with scalable flexibility using our advanced cell culture bioreactors. Our platform ensures efficient clone screening systems for optimal performance. ![clone-hero-250](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/clone-hero-250.webp?width=800&height=533&name=clone-hero-250.webp) ![clone-hero](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/clone-hero.webp?width=800&height=518&name=clone-hero.webp) ## Benefits   ![Culture\_Icon\_Check\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Check_Expressive_Green_01.png?width=54&height=54&name=Culture_Icon_Check_Expressive_Green_01.png) ##### Comprehensive clone screening Select the best cell clone or strain by evaluating larger experimental cohorts using our bioreactors. Make informed, data-driven decisions with our fleet of 250mL and 5L Culture bioreactors ![Culture\_Icon\_Check\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Check_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Check_Expressive_Green_01.png) ##### Real-time monitoring and expert insights Monitor transparent, real-time data from our cloud-connected bioreactors. With a \>95% success rate across 22,000+ runs, our team of experts ensures seamless technology transfer and reliable results.   ![Culture\_Icon\_Dollar\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Dollar_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Dollar_Expressive_Green_01.png) ##### Cost-effective screening Eliminate the need for capital equipment investment. Screen your bio clones, strains, and constructs using our state-of-the-art clone screening systems without additional infrastructure costs. ## Capabilities   ![Culture\_Icon\_Data\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Data_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Data_Expressive_Green_01.png) ##### Scaled-out bioreactor fleet With over 300 bioreactors (250mL and 5L), Culture enables you to expand your experimental scope and achieve the best outcomes for your clone screening and bio fermentation process needs. ![Culture\_Icon\_Data\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Data_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Data_Expressive_Green_01.png) ##### BSL-1 and BSL-2 compliance We culture and assay BSL-1 and BSL-2 organisms, ensuring versatility and compliance with industry standards.   ![Culture\_Icon\_Data\_Expressive\_Green\_01](https://www.culturebiosciences.com/hs-fs/hubfs/2026_Culture%20Biosciences/Icons/Culture_Icon_Data_Expressive_Green_01.png?width=55&height=55&name=Culture_Icon_Data_Expressive_Green_01.png) ##### Transparent, real-time monitoring Our experiment data sharing platform enables your team to monitor process trends and analytical results in real time. ## Our facility Our laboratories based in San Francisco are equipped with segregated modality suites, state-of-the-art bioreactors and analytical instrumentation, all operated by an experienced bioprocess development team. ![facility-1](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/facility-1.png?width=647&height=675&name=facility-1.png) ![facility-2](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/facility-2.png?width=648&height=330&name=facility-2.png) ![facility-3](https://www.culturebiosciences.com/hs-fs/hubfs/Website%202026/Images/facility-3.png?width=648&height=330&name=facility-3.png) ### 350+ 250mL and 5L bioreactors ### 20,000+ Bioreactor runs to date ### 70+ Customers have used Culture's services to date ## High quality & safety standards ##### Analytical capabilities - **Microbial bioprocess** \- Biomass quantification \- Metabolite analysis - **Mammalian bioprocess** \- Viability and cell counts \- Metabolite analysis - Host cell protein - **Protein** \- Titer quantification \- Monomer/aggregation quantification - **Viral vector** \- Capsid titer \- Viral genome titer \- Empty/full ratio ##### Segregated modality suites - **Mammalian** CHO and HEK - **Viral vector (AAV)** AAV generated by HEK transfection - **Microbial** Yeast, bacteria, and fungi - **Media** Media recipes to customer specifications ##### Rigorous standards - **Quality management systems (QMS)** Quality review of all runs and CAPA for major deviations - **Safety & security** BSL-2 and SOC2 compliant ## Our bioreactors At Culture, we custom-build our reactors to be cloud-connected and modular, making bioprocess scale-out, design, monitoring, and analysis as easy as possible. ### 250mL bench-scale single-use bioreactor Benchtop bioreactor for process development [Learn more](https://www.culturebiosciences.com/bioreactors/250ml?hsLang=en) ### 5L single-use bioreactor Our modular bioreactors are designed to be easily scaled up or down. [Learn more](https://www.culturebiosciences.com/bioreactors/5l?hsLang=en) ## Explore our other service packages ### Process development Upstream process development and optimization [Learn more](https://www.culturebiosciences.com/services/process-development?hsLang=en) ### Process characterization Accelerate process characterization development and cell culture optimization with scalable, data-driven experimentation. [Learn more](https://www.culturebiosciences.com/services/process-characterization?hsLang=en) ### Bioprocess modeling and simulation Create bioprocess digital twins for scalable biomanufacturing in collaboration with our data science team [Learn more](https://www.culturebiosciences.com/services/process-model-development?hsLang=en) ### Bioreactor scale-out Leverage bioreactor capacity when you need it [Learn more](https://www.culturebiosciences.com/services/scale-out-capacity?hsLang=en) ## Optimize your bioprocess with Culture [Schedule demo](https://www.culturebiosciences.com/request-demo?hsLang=en) ![Culture Logo black](https://www.culturebiosciences.com/hubfs/2026_Culture%20Biosciences/Logos/Culture%20Logo%20black.svg) ### Sign up for our newsletter and grow your insights with Culture. Smarter bioprocessing starts here. - Services Packages - [Clone, strain and construct screening](https://www.culturebiosciences.com/services/clone-strain-and-construct-screening) - [Process characterization](https://www.culturebiosciences.com/services/process-characterization) - [Process development](https://www.culturebiosciences.com/services/process-development) - [Bioprocess modeling
and simulation](https://www.culturebiosciences.com/services/process-model-development) - Products - [StratyxTM Bioreactor](https://www.culturebiosciences.com/stratyx) - [Console Software](https://www.culturebiosciences.com/#console) - [NexxysTM](https://www.culturebiosciences.com/nexxys) - [250mL bench-scale single-use bioreactor](https://www.culturebiosciences.com/bioreactors/250ml) - [5L single-use bioreactor](https://www.culturebiosciences.com/bioreactors/5l) - Applications - [Synthetic biology applications](https://www.culturebiosciences.com/applications/synthetic-biology) - [Protein therapeutics](https://www.culturebiosciences.com/applications/protein-therapeutics) - [Viral vectors](https://www.culturebiosciences.com/applications/viral-vectors) - Resources - [White papers](https://www.culturebiosciences.com/resources/tag/white-paper) - [Case studies](https://www.culturebiosciences.com/resources/tag/case-study) - [Blog posts](https://www.culturebiosciences.com/resources/tag/blog-post) - [Announcements](https://www.culturebiosciences.com/resources/tag/announcement) - [Webinars](https://www.culturebiosciences.com/resources/tag/webinar) - [Videos](https://www.culturebiosciences.com/resources/tag/video) - [All resources](https://www.culturebiosciences.com/resources) - Company - [About](https://www.culturebiosciences.com/about) - [Careers](https://www.culturebiosciences.com/careers) - [Contact](https://www.culturebiosciences.com/contact) - [LinkedIn](https://www.linkedin.com/company/18240703/admin/feed/posts/) All systems operational... © 2026 Culture Biosciences [Terms](https://www.culturebiosciences.com/terms-of-service?hsLang=en) [Privacy](https://www.culturebiosciences.com/privacy-policy?hsLang=en)