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Smarter Bioprocessing Starts Here: Explore the Cytiva x Culture Global Collaboration

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Services

Clone, strain &
construct screening

Benefits

 
Comprehensive clone screening
Comprehensive clone screening

Select the best cell clone or strain by evaluating larger experimental cohorts using our bioreactors. Make informed, data-driven decisions with our fleet of 250mL and 5L Culture bioreactors

Real-time monitoring and expert insights
Real-time monitoring and expert insights

Monitor transparent, real-time data from our cloud-connected bioreactors. With a >95% success rate across 22,000+ runs, our team of experts ensures seamless technology transfer and reliable results.

 
Cost-effective screening
Cost-effective screening

Eliminate the need for capital equipment investment. Screen your bio clones, strains, and constructs using our state-of-the-art clone screening systems without additional infrastructure costs.

Capabilities

 
Scaled-out bioreactor fleet
Scaled-out bioreactor fleet

With over 300 bioreactors (250mL and 5L), Culture enables you to expand your experimental scope and achieve the best outcomes for your clone screening and bio fermentation process needs.

BSL-1 and BSL-2 compliance
BSL-1 and BSL-2 compliance

We culture and assay BSL-1 and BSL-2 organisms, ensuring versatility and compliance with industry standards.

 
Transparent, real-time monitoring
Transparent, real-time monitoring

Our experiment data sharing platform enables your team to monitor process trends and analytical results in real time.

Our facility

Our laboratories based in San Francisco are equipped with segregated modality suites, state-of-the-art bioreactors and analytical instrumentation, all operated by an experienced bioprocess development team.

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350+

250mL and 5L bioreactors

20,000+

Bioreactor runs to date

70+

Customers have used Culture's services to date

High quality & safety standards

Analytical capabilities
  • Microbial bioprocess
    - Biomass quantification
    - Metabolite analysis
  • Mammalian bioprocess
    - Viability and cell counts
    - Metabolite analysis
    - Host cell protein
  • Protein
    - Titer quantification
    - Monomer/aggregation quantification
  • Viral vector
    - Capsid titer
    - Viral genome titer
    - Empty/full ratio
Segregated modality suites
  • Mammalian
    CHO and HEK
  • Viral vector (AAV)
    AAV generated by HEK transfection
  • Microbial
    Yeast, bacteria, and fungi
  • Media
    Media recipes to customer specifications
Rigorous standards
  • Quality management systems (QMS)
    Quality review of all runs and CAPA for major deviations
  • Safety & security
    BSL-2 and SOC2 compliant

Our bioreactors

At Culture, we custom-build our modular reactors with cloud-connected controllers, making bioprocess scale-out, design, monitoring, and analysis as easy as possible.
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250mL bench-scale single-use bioreactor

Benchtop bioreactor for process development

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5L single-use bioreactor

Our modular bioreactors are designed to be easily scaled up or down.

Explore our other service packages

Process development

Upstream process development and optimization

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Process characterization

Accelerate process characterization development and cell culture optimization with scalable, data-driven experimentation.

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Bioprocess modeling and simulation

Create bioprocess digital twins for scalable biomanufacturing in collaboration with our data science team

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Bioreactor scale-out

Leverage bioreactor capacity when you need it

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Optimize your bioprocess with Culture