Why Mass Balance Is Important

Accounting for all inputs and outputs of a fermentation is crucial to accurately measure the total amount of product in a reactor. But, to do so, many fermentation systems require installation of additional, expensive equipment and time to compile various data streams. The problem is that without an accurate measurement of total product by mass, you run the risk of:

• Inaccurate performance metrics
• A false estimate of strain performance
• Developing a fermentation process that is not commercially viable

‍

How Culture Ensures Closed Mass Balances

Culture's system eliminates these risks by tracking mass-based measurements using distinct features, including:

• Hardware such as mass flow controllers, off-gas sensors, and feed scales to accurately measure every input and output (liquid and gas) for each fermentation process
• Custom control software that enables all inputs to the reactor to be delivered accurately and all manual additions or removals to be tracked

‍